Taipei Veterans General Hospital · Division of Integrative Medicine
National Yang Ming Chiao Tung University · Academic & Clinical Website
中文EN
Projects

Research Projects

Chinese and English project titles are presented on separate pages. This page contains the English version.

National Science and Technology Council Projects

  1. Analysis of the efficacy and mechanism of electroacupuncture at GB20 for dry eye disease through regulation of AQP5, muscarinic receptors, and exosomal miRNA-mediated NF-κB/MAPK pathways (NSTC 114-2628-B-A49-006-MY3), PI, 2025.08–2028.07, NSTC
  2. Systematic dissection of exosome-miRNA and transcriptome profiling of dry eye syndrome and Sjögren’s syndrome for alleviating sicca symptoms (NSTC 113-2320-B-A49-029), PI, 2024.08–2025.07, NSTC, ClinicalTrials.gov: NCT06475027
  3. Application of large language models to genomic phasing and haplotype analysis (NSTC 113-2221-E-468-008), Co-PI, 2024.08–2025.07, NSTC
  4. Using the oral microbiota to evaluate the immediate and long-term efficacy of acupuncture at GB20 plus BL2 for ocular and oral dryness symptoms in dry eye syndrome and Sjögren’s syndrome (NSTC-111-2320-B-075-006-MY2), PI, 2022.08–2024.07, NSTC, ClinicalTrials.gov: NCT04877483
  5. Applying a service-learning model to evaluate medical humanities education through traditional medicine services and professional training in overseas remote areas (MOST-109-2511-H-075-002), PI, 2020.08–2022.07, MOST
  6. Application of bioinformatics to Shanghan formulas: exploring the prescription logic of classical formulas (NSC97-2815-C-039-061-B), Undergraduate research trainee, 2008.07–2009.02, NSC

Taipei Veterans General Hospital Projects

  1. Application of the herbal tea TBDESJS in an integrated lipid metabolism and immune-cell response platform for Sjögren’s syndrome and dry eye syndrome (V115C-111), PI, 2026.01–2026.12, Taipei Veterans General Hospital
  2. Systemic proteomic analysis of plasma exosomes to explore immunomodulatory signatures in Sjögren’s syndrome and dry eye syndrome (V114C-078), PI, 2025.01–2025.12, Taipei Veterans General Hospital, ClinicalTrials.gov: NCT06771427
  3. To evaluate the Chinese herbal tea VGH-DESJS-1 in ocular and oral dryness symptoms of dry eye syndrome and Sjögren’s syndrome (Year 2: exosome-based investigation of potential mechanisms for alleviating sicca symptoms) (V113C-087), PI, 2024.01–2024.12, Taipei Veterans General Hospital, ClinicalTrials.gov: NCT06475027
  4. To evaluate the Chinese herbal tea VGH-DESJS-1 in ocular and oral dryness symptoms of dry eye syndrome and Sjögren’s syndrome (V112C-190), PI, 2023.01–2023.12, Taipei Veterans General Hospital, ClinicalTrials.gov: NCT05656196
  5. Using DNA exome sequencing to explore the association among gene sequence, TCM constitution, tongue diagnosis, and pulse diagnosis in Sjögren’s syndrome (Year 2: integrated functional proteomics and oral microbiome) (V109B-034), PI, 2020.01–2020.12, Taipei Veterans General Hospital, ClinicalTrials.gov: NCT03935373
  6. Using DNA exome sequencing to explore the association among gene sequence, TCM constitution, tongue diagnosis, and pulse diagnosis in Sjögren’s syndrome (V108B-031), PI, 2019.01–2019.12, Taipei Veterans General Hospital, ClinicalTrials.gov: NCT03935373
  7. Clinical nursing practice program for traditional Chinese medicine (V106EP-009), Co-PI, 2017.06–2017.12, Taipei Veterans General Hospital
  8. Using an IFN-γ induced human submaxillary salivary gland cell model to investigate mitochondrial antioxidant mechanisms of the ten most commonly prescribed single herbs for Sjögren’s syndrome from the National Health Insurance Research Database (V106A-006), PI, 2017.01–2017.12, Taipei Veterans General Hospital

Participating Projects

  1. Immune-gene regulatory mechanisms of the Chinese herbal formula SS-1 for sicca syndrome (MOST 105-2325-B-039-006), PhD student and collaborative researcher, 2016.05–2016.04, MOST National Biotechnology and Pharmaceutical Program, ClinicalTrials.gov: NCT02855658
  2. Randomized double-blind clinical trial of the Chinese herbal formula SS-1 for sicca syndrome and investigation of its mechanisms (NSC103-2325-B-182-010), PhD student and collaborative researcher, 2014.02–2016.07, NSC National Biotechnology and Pharmaceutical Program, ClinicalTrials.gov: NCT02110446