Research Directions and Academic Expertise
From Sjögren’s syndrome and dry eye to systemic autoimmune disease, integrating clinical questions, data platforms, and integrative medical approaches. Click each theme for a detailed page.
Research Overview
Integrative Research in Sjögren’s Syndrome and Dry Eye
A core research line centered on Sjögren’s syndrome and dry eye, integrating herbal medicine, acupuncture, HRV, tongue/pulse diagnosis, ocular surface assessment, and multimodal objective measurements.
Integrative Medicine Research in Rheumatic and Autoimmune Diseases
Extends to systemic lupus erythematosus, rheumatoid arthritis, ankylosing spondylitis, IgG4-related disease, and other immune-mediated rheumatic disorders.
Clinical Trial Design and Translational Application
Combines randomized trials, case-oriented research, and real-world evidence, with emphasis on moving from clinical questions back to clinical application.
Research in Systemic Lupus Erythematosus
Focuses on lupus and its renal, cardiovascular, and symptom-related dimensions, alongside integrative medical interventions.
TCM Formula and Prescription Database Systems
Uses prescription databases and national health data to analyze formula patterns, core prescriptions, and clinical application models.
Bioinformatics and Data Mining
Combines bioinformatics, data mining, multi-omics, and clinical data to develop analyzable and translatable research platforms.
TCM Classics, Textual Organization, and Theoretical Interpretation
Builds from TCM classics, pattern theory, and conceptual interpretation, while linking them to modern research language and clinical teaching.
Academic Expertise and Integrative Capabilities
A clinical and translational research portfolio centered on rheumatology, Sjögren’s disease, dry eye disease, integrative medicine, objective measurement, data science, and medical education.
Autoimmune disease and Sjögren’s disease
Clinical care, stratification, and integrative treatment for Sjögren’s disease, dry eye disease, SLE, IgG4-related disease, and related rheumatic conditions.
Integrative Chinese-Western interventions
Research on herbal medicine, acupuncture, formula-based interventions, lifestyle guidance, and modern medical care for symptom burden and immune dysregulation.
Clinical trials and real-world evidence
Randomized trials, external validation, case-series design, and real-world data analyses anchored in clinical questions.
Objective measurement and multimodal data
Integration of Schirmer test, OSDI, TBUT, HRV, tongue and pulse data, imaging, questionnaires, microbiome, and multi-omics data.
AI, data mining, and decision support
Machine learning, multimodal models, and clinical decision support tools for disease classification, response prediction, and research platforms.
TCM theory, classics, and education
Translation of TCM basic theory, pattern differentiation, classical interpretation, and lecture materials into searchable educational resources.
Core Research Approach
- Begin with real clinical questions and convert them into testable research hypotheses.
- Evaluate outcomes using both objective measurements and patient-reported outcomes.
- Connect TCM pattern reasoning with modern immunology and data science.
- Translate findings back into clinical care, student training, and patient education.